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That difference affects liability, documentation, and insurance routes

Looking at the reactions that use vitamin B 12 (Figure 1) , 3 an elevated methylmalonic acid level is clearly more specific for vitamin B 12 deficiency than an elevated homocysteine level

There are also many studies on the effectiveness of methyl B12 on improved function in a plethora of conditions, which you can read about in our article about B12 forms

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This is especially true when administered under proper medical supervision

Instead of overcoming the metabolic adaptation, higher doses frequently exacerbate side effects like nausea, fatigue, and gastrointestinal distress